30mg · 30-count · Mental Health · Brand: Cymbalta · Generic available
| Pharmacy | Cash Price | Per-30-Day Equiv. |
|---|---|---|
| Costco Cheapest | $8.50 | $8.50 |
| Walmart | $10.00 | $10.00 |
| Kroger | $11.00 | $11.00 |
| Target | $11.25 | $11.25 |
| Rite Aid | $23.50 | $23.50 |
| CVS | $24.99 | $24.99 |
| Walgreens | $26.00 | $26.00 |
The generic form of Duloxetine (Duloxetine HCl) contains the same active ingredient and is bioequivalent to the brand. Ask your pharmacist to dispense the generic — it works the same way at a fraction of the cost.
Tip: In most states, pharmacists can substitute a generic unless your prescriber writes "dispense as written" (DAW).
Duloxetine is prescribed to treat depression, anxiety, and related mood disorders. It is sold under the brand name Cymbalta and is available as the generic Duloxetine HCl. A standard supply is 30 30mg.
Pharmacy pricing is not regulated in the United States, so retailers set their own cash prices. Large retailers like Walmart and Costco typically offer lower prices on generics because they use prescriptions as a traffic driver. Chain pharmacies like CVS and Walgreens tend to charge significantly more.
Antidepressants and antipsychotics vary widely in price. Most SSRIs and SNRIs have affordable generics, while newer branded medications can cost hundreds per month.
Shop around. The cheapest pharmacy (Costco at $8.50) charges significantly less than the most expensive option ($26.00). A quick call can save you real money.
Ask for the generic. If your doctor prescribed the brand-name Cymbalta, ask your pharmacist whether the generic Duloxetine HCl is available. In most states, pharmacists can substitute a generic unless the prescriber writes 'dispense as written.'
Use a discount card. Services like GoodRx, SingleCare, and WellRx can sometimes negotiate prices lower than retail cash. The estimated GoodRx low for Duloxetine is around $7.40.
Coverage depends on your specific plan and formulary. Most mental health medications are covered under standard health insurance, typically in Tier 1 or Tier 2. If your copay is higher than the cash price above, it may be cheaper to pay out of pocket — ask your pharmacist to compare.
Prices represent estimated retail cash prices for Duloxetine 30mg (30-count) as of 2026. Actual prices may vary. RxCostCheck does not collect or sell your health data. Learn more →
How much does Duloxetine cost without insurance?
Without insurance, Duloxetine 30mg (30-count) ranges from $8.50 at Costco to $26.00. With a GoodRx discount card, the price can be as low as $7.40.
Where is the cheapest place to fill Duloxetine?
Costco currently offers the lowest cash price at $8.50 for 30 30mg.
Is there a generic for Duloxetine?
Yes — the generic Duloxetine HCl is available and bioequivalent to Cymbalta. Ask your pharmacist to dispense the generic to save money.
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