40mg · 30-count · Acid Reflux · Brand: Nexium · Generic available
| Pharmacy | Cash Price | Per-30-Day Equiv. |
|---|---|---|
| Costco Cheapest | $6.80 | $6.80 |
| Walmart | $8.00 | $8.00 |
| Kroger | $9.00 | $9.00 |
| Target | $9.49 | $9.49 |
| Rite Aid | $18.50 | $18.50 |
| CVS | $18.99 | $18.99 |
| Walgreens | $20.00 | $20.00 |
The generic form of Esomeprazole (Esomeprazole Mg) contains the same active ingredient and is bioequivalent to the brand. Ask your pharmacist to dispense the generic — it works the same way at a fraction of the cost.
Tip: In most states, pharmacists can substitute a generic unless your prescriber writes "dispense as written" (DAW).
Esomeprazole is prescribed to reduce stomach acid production and treat acid reflux, GERD, and ulcers. It is sold under the brand name Nexium and is available as the generic Esomeprazole Mg. A standard supply is 30 40mg.
Pharmacy pricing is not regulated in the United States, so retailers set their own cash prices. Large retailers like Walmart and Costco typically offer lower prices on generics because they use prescriptions as a traffic driver. Chain pharmacies like CVS and Walgreens tend to charge significantly more.
Proton pump inhibitors (PPIs) and H2 blockers are widely used. Generic versions are available and usually cost under $10/month at cash prices.
Shop around. The cheapest pharmacy (Costco at $6.80) charges significantly less than the most expensive option ($20.00). A quick call can save you real money.
Ask for the generic. If your doctor prescribed the brand-name Nexium, ask your pharmacist whether the generic Esomeprazole Mg is available. In most states, pharmacists can substitute a generic unless the prescriber writes 'dispense as written.'
Use a discount card. Services like GoodRx, SingleCare, and WellRx can sometimes negotiate prices lower than retail cash. The estimated GoodRx low for Esomeprazole is around $5.60.
Coverage depends on your specific plan and formulary. Most acid reflux medications are covered under standard health insurance, typically in Tier 1 or Tier 2. If your copay is higher than the cash price above, it may be cheaper to pay out of pocket — ask your pharmacist to compare.
Prices represent estimated retail cash prices for Esomeprazole 40mg (30-count) as of 2026. Actual prices may vary. RxCostCheck does not collect or sell your health data. Learn more →
How much does Esomeprazole cost without insurance?
Without insurance, Esomeprazole 40mg (30-count) ranges from $6.80 at Costco to $20.00. With a GoodRx discount card, the price can be as low as $5.60.
Where is the cheapest place to fill Esomeprazole?
Costco currently offers the lowest cash price at $6.80 for 30 40mg.
Is there a generic for Esomeprazole?
Yes — the generic Esomeprazole Mg is available and bioequivalent to Nexium. Ask your pharmacist to dispense the generic to save money.
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