20mg · 30-count · Acid Reflux · Brand: Prilosec · Generic available
| Pharmacy | Cash Price | Per-30-Day Equiv. |
|---|---|---|
| Walmart Cheapest | $4.00 | $4.00 |
| Kroger | $4.50 | $4.50 |
| Costco | $5.49 | $5.49 |
| Target | $7.99 | $7.99 |
| Rite Aid | $10.50 | $10.50 |
| CVS | $10.99 | $10.99 |
| Walgreens | $11.50 | $11.50 |
Omeprazole is prescribed to reduce stomach acid production and treat acid reflux, GERD, and ulcers. It is sold under the brand name Prilosec and is available as the generic Omeprazole. A standard supply is 30 20mg.
Pharmacy pricing is not regulated in the United States, so retailers set their own cash prices. Large retailers like Walmart and Costco typically offer lower prices on generics because they use prescriptions as a traffic driver. Chain pharmacies like CVS and Walgreens tend to charge significantly more.
Proton pump inhibitors (PPIs) and H2 blockers are widely used. Generic versions are available and usually cost under $10/month at cash prices.
Shop around. The cheapest pharmacy (Walmart at $4.00) charges significantly less than the most expensive option ($11.50). A quick call can save you real money.
Ask for the generic. If your doctor prescribed the brand-name Prilosec, ask your pharmacist whether the generic Omeprazole is available. In most states, pharmacists can substitute a generic unless the prescriber writes 'dispense as written.'
Use a discount card. Services like GoodRx, SingleCare, and WellRx can sometimes negotiate prices lower than retail cash. The estimated GoodRx low for Omeprazole is around $3.20.
Coverage depends on your specific plan and formulary. Most acid reflux medications are covered under standard health insurance, typically in Tier 1 or Tier 2. If your copay is higher than the cash price above, it may be cheaper to pay out of pocket — ask your pharmacist to compare.
Prices represent estimated retail cash prices for Omeprazole 20mg (30-count) as of 2026. Actual prices may vary. RxCostCheck does not collect or sell your health data. Learn more →
How much does Omeprazole cost without insurance?
Without insurance, Omeprazole 20mg (30-count) ranges from $4.00 at Walmart to $11.50. With a GoodRx discount card, the price can be as low as $3.20.
Where is the cheapest place to fill Omeprazole?
Walmart currently offers the lowest cash price at $4.00 for 30 20mg.
Is there a generic for Omeprazole?
Yes — the generic Omeprazole is available and bioequivalent to Prilosec. Ask your pharmacist to dispense the generic to save money.
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