⚕️ Prices shown are estimated cash prices for informational purposes only. Always verify with your pharmacy. Not medical advice.

Ondansetron Price Comparison

4mg · 10-count · Digestive · Brand: Zofran · Generic available

Cheapest Cash Price
$3.66
at Costco · 4mg · 10-count
GoodRx Low Est.
$3.18
with discount card
Cash Price by Pharmacy — 4mg · 10-count
PharmacyCash PricePer-30-Day Equiv.
Costco Cheapest$3.66$3.66
Walmart$4.14$4.14
Kroger$4.70$4.70
Target$5.39$5.39
Rite Aid$14.85$14.85
CVS$15.54$15.54
Walgreens$16.58$16.58

Brand vs. Generic: Zofran vs. Ondansetron HCl

The generic form of Ondansetron (Ondansetron HCl) contains the same active ingredient and is bioequivalent to the brand. Ask your pharmacist to dispense the generic — it works the same way, typically at a fraction of the brand-name cost.

Brand: Zofran
Varies
brand pricing not tracked separately
Generic: Ondansetron HCl
$3.66
cheapest at Costco

Tip: In most states, pharmacists can substitute a generic unless your prescriber writes "dispense as written" (DAW).

About Ondansetron

Ondansetron (4mg) is sold under the brand name Zofran and the generic Ondansetron HCl. A standard supply tracked here is 10 units at 4mg.

Why Do Prices Vary by Pharmacy?

Pharmacy pricing is not regulated in the United States, so retailers set their own cash prices. Large retailers like Walmart and Costco typically offer lower prices on generics because they use prescriptions as a traffic driver. Chain pharmacies like CVS and Walgreens tend to charge more for the same medication.

Digestive medications range from short courses to long-term daily use, so check whether your prescription is for acute or maintenance therapy.

How to Pay Less for Ondansetron

Shop around. The cheapest pharmacy tracked here (Costco at $3.66) charges meaningfully less than the most expensive option ($16.58). A quick call can save real money.

Ask for the generic. If your doctor prescribed the brand-name Zofran, ask your pharmacist whether a generic is available. In most states, pharmacists can substitute a generic unless the prescriber writes "dispense as written."

Use a discount card. Services like GoodRx, SingleCare, and WellRx can sometimes negotiate prices lower than retail cash. The estimated low price for Ondansetron is around $3.18.

💡 Tip: Walmart's $4 and $10 generic drug program covers many common generics. Call your local Walmart pharmacy to ask if Ondansetron is on their list.

Does Insurance Cover Ondansetron?

Coverage depends on your specific plan and formulary. Most medications in this category are covered under standard health insurance, typically in Tier 1 or Tier 2. If your copay is higher than the cash price above, it may be cheaper to pay out of pocket — ask your pharmacist to compare.

About This Price Data

Prices shown are estimated retail cash prices modeled from CMS's public NADAC (National Average Drug Acquisition Cost) dataset, cross-referenced against typical major-chain retail markups. Actual prices vary by location and change frequently. RxCostCheck does not collect or sell your health data. Learn more →

Frequently Asked Questions

How much does Ondansetron cost without insurance?

Without insurance, Ondansetron (4mg) ranges from $3.66 at Costco to $16.58 at Walgreens. With a discount card, the price can be as low as $3.18.

Where is the cheapest place to fill Ondansetron?

Costco currently offers the lowest estimated cash price at $3.66 for 10 4mg.

Is there a generic for Ondansetron?

Yes — the generic Ondansetron HCl is available and bioequivalent to Zofran. Ask your pharmacist to dispense the generic to save money.

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