250mg · 6-count · Antibiotics · Brand: Zithromax · Generic available
| Pharmacy | Cash Price | Per-30-Day Equiv. |
|---|---|---|
| Costco Cheapest | $7.80 | $39.00 |
| Walmart | $9.00 | $45.00 |
| Target | $9.99 | $49.95 |
| Kroger | $10.00 | $50.00 |
| Rite Aid | $14.00 | $70.00 |
| CVS | $14.99 | $74.95 |
| Walgreens | $15.50 | $77.50 |
Azithromycin is a prescription antibiotic used to treat bacterial infections. It is sold under the brand name Zithromax and is available as the generic Azithromycin. A standard supply is 6 250mg.
Pharmacy pricing is not regulated in the United States, so retailers set their own cash prices. Large retailers like Walmart and Costco typically offer lower prices on generics because they use prescriptions as a traffic driver. Chain pharmacies like CVS and Walgreens tend to charge significantly more.
Antibiotics are typically short-course prescriptions. Most common antibiotics are available as generics at very low cash prices — many are on Walmart's $4 generic program.
Azithromycin belongs to a class of medications called macrolide antibiotics. It's prescribed for a range of bacterial infections and is often used as a short course — sometimes as few as five doses (a 'Z-Pack') — which is why it's typically sold in a small count like the 6-count supply shown above rather than a 30-day bottle. Because it concentrates in tissue and continues working after the last dose, prescribers sometimes choose it specifically to shorten how many days a patient needs to remember to take a pill, which can be a meaningful practical advantage for some patients over an antibiotic requiring twice-daily dosing for a week or more.
Shop around. The cheapest pharmacy (Costco at $7.80) charges significantly less than the most expensive option ($15.50). A quick call can save you real money.
Ask for the generic. If your doctor prescribed the brand-name Zithromax, ask your pharmacist whether the generic Azithromycin is available. In most states, pharmacists can substitute a generic unless the prescriber writes 'dispense as written.'
Use a discount card. Services like GoodRx, SingleCare, and WellRx can sometimes negotiate prices lower than retail cash. The estimated GoodRx low for Azithromycin is around $7.00.
As a long-generic antibiotic used for short courses, azithromycin has no manufacturer copay card program — pricing differences between pharmacies reflect retail markup rather than a brand-vs-generic gap.
Coverage depends on your specific plan and formulary. Most antibiotics medications are covered under standard health insurance, typically in Tier 1 or Tier 2. If your copay is higher than the cash price above, it may be cheaper to pay out of pocket — ask your pharmacist to compare. Prior authorization is essentially never required for azithromycin given its decades-long generic status and its role as a standard short-course antibiotic.
Prices represent estimated retail cash prices for Azithromycin 250mg (6-count) as of 2026. Actual prices may vary. RxCostCheck does not collect or sell your health data. Learn more →
How much does Azithromycin cost without insurance?
Without insurance, Azithromycin 250mg (6-count) ranges from $7.80 at Costco to $15.50. With a GoodRx discount card, the price can be as low as $7.00.
Where is the cheapest place to fill Azithromycin?
Costco typically offers the lowest cash price at $7.80 for 6 250mg.
Is there a generic for Azithromycin?
Yes — the generic Azithromycin is available and bioequivalent to Zithromax. Ask your pharmacist to dispense the generic to save money.
What if my insurance doesn't cover Azithromycin at all?
Ask your prescriber whether a covered therapeutic alternative in the same drug class exists, or ask your pharmacist about a formulary exception or medical-necessity appeal — some plans will cover an otherwise-excluded drug once that documentation is on file. In the meantime, the cash and discount-card pricing shown above is usually the fastest fallback.
Does a 90-day supply of Azithromycin cost less than three 30-day fills?
Often, yes — many pharmacies and insurance plans price a 90-day fill at a lower effective per-dose cost than separate 30-day fills, and some mail-order pharmacy benefits are built specifically around 90-day supplies. Ask your pharmacist or insurer whether a 90-day option is available for this medication before assuming the count shown above is your only choice.
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