250/50mcg · 1-count · Asthma · Brand: Advair · Generic available
| Pharmacy | Cash Price | Per-30-Day Equiv. |
|---|---|---|
| Costco Cheapest | $85.00 | $2550.00 |
| Walmart | $98.00 | $2940.00 |
| Target | $99.99 | $2999.70 |
| Kroger | $102.00 | $3060.00 |
| Rite Aid | $128.00 | $3840.00 |
| CVS | $129.99 | $3899.70 |
| Walgreens | $134.00 | $4020.00 |
The generic form of Fluticasone-Salmeterol Generic (Fluticasone/Salmeterol) contains the same active ingredient and is bioequivalent to the brand. Ask your pharmacist to dispense the generic — it works the same way at a fraction of the cost.
Tip: In most states, pharmacists can substitute a generic unless your prescriber writes "dispense as written" (DAW).
Fluticasone-Salmeterol Generic is prescribed to treat asthma and other respiratory conditions. It is sold under the brand name Advair and is available as the generic Fluticasone/Salmeterol. A standard supply is 1 250/50mcg.
Pharmacy pricing is not regulated in the United States, so retailers set their own cash prices. Large retailers like Walmart and Costco typically offer lower prices on generics because they use prescriptions as a traffic driver. Chain pharmacies like CVS and Walgreens tend to charge significantly more.
Inhaler prices have been a major drug pricing focus. Generic inhalers are now available for some formulations, offering meaningful savings over brand-name options.
Fluticasone-Salmeterol Generic belongs to a class of medications called ICS/LABA combination inhalers. The inhaled corticosteroid component reduces airway inflammation while the long-acting beta agonist keeps airways open over a longer duration than a rescue inhaler. It's a maintenance medication for asthma or COPD meant to be used on a fixed schedule, not as a rescue treatment during a sudden flare-up, so patients on it are typically also prescribed a separate short-acting rescue inhaler for acute symptoms.
Shop around. The cheapest pharmacy (Costco at $85.00) charges significantly less than the most expensive option ($134.00). A quick call can save you real money.
Ask for the generic. If your doctor prescribed the brand-name Advair, ask your pharmacist whether the generic Fluticasone/Salmeterol is available. In most states, pharmacists can substitute a generic unless the prescriber writes 'dispense as written.'
Use a discount card. Services like GoodRx, SingleCare, and WellRx can sometimes negotiate prices lower than retail cash. The estimated GoodRx low for Fluticasone-Salmeterol Generic is around $72.00.
Generic fluticasone-salmeterol has narrowed the price gap with the original brand considerably since it reached the market, and while the brand version has historically offered manufacturer copay cards for eligible commercially insured patients, those programs typically exclude Medicare and Medicaid patients under federal anti-kickback rules — ask your pharmacist whether the generic is being dispensed, since that alone often closes most of the price gap.
Coverage depends on your specific plan and formulary. Most asthma medications are covered under standard health insurance, typically in Tier 1 or Tier 2. If your copay is higher than the cash price above, it may be cheaper to pay out of pocket — ask your pharmacist to compare. Prior authorization and step therapy are more common for combination respiratory inhalers like this one than for single-ingredient inhalers, since insurers often want documentation that a less expensive single-agent option was tried first.
Prices represent estimated retail cash prices for Fluticasone-Salmeterol Generic 250/50mcg (1-count) as of 2026. Actual prices may vary. RxCostCheck does not collect or sell your health data. Learn more →
How much does Fluticasone-Salmeterol Generic cost without insurance?
Without insurance, Fluticasone-Salmeterol Generic 250/50mcg (1-count) ranges from $85.00 at Costco to $134.00. With a GoodRx discount card, the price can be as low as $72.00.
Where is the cheapest place to fill Fluticasone-Salmeterol Generic?
Costco typically offers the lowest cash price at $85.00 for 1 250/50mcg.
Is there a generic for Fluticasone-Salmeterol Generic?
Yes — the generic Fluticasone/Salmeterol is available and bioequivalent to Advair. Ask your pharmacist to dispense the generic to save money.
What if my insurance doesn't cover Fluticasone-Salmeterol Generic at all?
Ask your prescriber whether a covered therapeutic alternative in the same drug class exists, or ask your pharmacist about a formulary exception or medical-necessity appeal — some plans will cover an otherwise-excluded drug once that documentation is on file. In the meantime, the cash and discount-card pricing shown above is usually the fastest fallback.
Does a 90-day supply of Fluticasone-Salmeterol Generic cost less than three 30-day fills?
Often, yes — many pharmacies and insurance plans price a 90-day fill at a lower effective per-dose cost than separate 30-day fills, and some mail-order pharmacy benefits are built specifically around 90-day supplies. Ask your pharmacist or insurer whether a 90-day option is available for this medication before assuming the count shown above is your only choice.
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