2mg · 30-count · Diabetes · Brand: Amaryl · Generic available
| Pharmacy | Cash Price | Per-30-Day Equiv. |
|---|---|---|
| Costco Cheapest | $3.90 | $3.90 |
| Walmart | $4.00 | $4.00 |
| Kroger | $4.50 | $4.50 |
| Target | $5.25 | $5.25 |
| Rite Aid | $13.50 | $13.50 |
| CVS | $14.50 | $14.50 |
| Walgreens | $15.00 | $15.00 |
Glimepiride is used to manage blood sugar levels in people with type 2 diabetes. It is sold under the brand name Amaryl and is available as the generic Glimepiride. A standard supply is 30 2mg.
Pharmacy pricing is not regulated in the United States, so retailers set their own cash prices. Large retailers like Walmart and Costco typically offer lower prices on generics because they use prescriptions as a traffic driver. Chain pharmacies like CVS and Walgreens tend to charge significantly more.
Diabetes medications can vary widely in price. Generic versions are available for most first-line treatments. Walmart's $4 program covers several common diabetes generics.
Glimepiride belongs to a class of medications called sulfonylureas. It works by stimulating the pancreas to release more insulin, which is a different mechanism than metformin, and is typically prescribed for type 2 diabetes when diet, exercise, and first-line medications haven't fully controlled blood sugar on their own. Sulfonylureas like glimepiride carry a documented risk of low blood sugar (hypoglycemia), particularly if a dose is taken without eating enough afterward, which is a class-wide safety consideration your prescriber will have discussed when starting you on it or adjusting your dose.
Shop around. The cheapest pharmacy (Costco at $3.90) charges significantly less than the most expensive option ($15.00). A quick call can save you real money.
Ask for the generic. If your doctor prescribed the brand-name Amaryl, ask your pharmacist whether the generic Glimepiride is available. In most states, pharmacists can substitute a generic unless the prescriber writes 'dispense as written.'
Use a discount card. Services like GoodRx, SingleCare, and WellRx can sometimes negotiate prices lower than retail cash. The estimated GoodRx low for Glimepiride is around $3.20.
Glimepiride has been an inexpensive generic for years, with no manufacturer copay card involved — the cash prices above already reflect standard low-cost generic pricing for this drug class.
Coverage depends on your specific plan and formulary. Most diabetes medications are covered under standard health insurance, typically in Tier 1 or Tier 2. If your copay is higher than the cash price above, it may be cheaper to pay out of pocket — ask your pharmacist to compare. Prior authorization is uncommon for glimepiride given its long generic history and low cost relative to many newer diabetes medications, which most formularies place in a lower cost-sharing tier.
Prices represent estimated retail cash prices for Glimepiride 2mg (30-count) as of 2026. Actual prices may vary. RxCostCheck does not collect or sell your health data. Learn more →
How much does Glimepiride cost without insurance?
Without insurance, Glimepiride 2mg (30-count) ranges from $3.90 at Costco to $15.00. With a GoodRx discount card, the price can be as low as $3.20.
Where is the cheapest place to fill Glimepiride?
Costco typically offers the lowest cash price at $3.90 for 30 2mg.
Is there a generic for Glimepiride?
Yes — the generic Glimepiride is available and bioequivalent to Amaryl. Ask your pharmacist to dispense the generic to save money.
What if my insurance doesn't cover Glimepiride at all?
Ask your prescriber whether a covered therapeutic alternative in the same drug class exists, or ask your pharmacist about a formulary exception or medical-necessity appeal — some plans will cover an otherwise-excluded drug once that documentation is on file. In the meantime, the cash and discount-card pricing shown above is usually the fastest fallback.
Does a 90-day supply of Glimepiride cost less than three 30-day fills?
Often, yes — many pharmacies and insurance plans price a 90-day fill at a lower effective per-dose cost than separate 30-day fills, and some mail-order pharmacy benefits are built specifically around 90-day supplies. Ask your pharmacist or insurer whether a 90-day option is available for this medication before assuming the count shown above is your only choice.
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