25mg · 30-count · Blood Pressure · Brand: Microzide · Generic available
| Pharmacy | Cash Price | Per-30-Day Equiv. |
|---|---|---|
| Costco Cheapest | $3.40 | $3.40 |
| Walmart | $4.00 | $4.00 |
| Kroger | $4.00 | $4.00 |
| Target | $4.75 | $4.75 |
| Rite Aid | $10.50 | $10.50 |
| CVS | $10.99 | $10.99 |
| Walgreens | $11.50 | $11.50 |
The generic form of Hydrochlorothiazide (HCTZ) contains the same active ingredient and is bioequivalent to the brand. Ask your pharmacist to dispense the generic — it works the same way at a fraction of the cost.
Tip: In most states, pharmacists can substitute a generic unless your prescriber writes "dispense as written" (DAW).
Hydrochlorothiazide is prescribed to control high blood pressure (hypertension) and protect heart health. It is sold under the brand name Microzide and is available as the generic HCTZ. A standard supply is 30 25mg.
Pharmacy pricing is not regulated in the United States, so retailers set their own cash prices. Large retailers like Walmart and Costco typically offer lower prices on generics because they use prescriptions as a traffic driver. Chain pharmacies like CVS and Walgreens tend to charge significantly more.
Most blood pressure medications have been off-patent for years, making their generics extremely affordable. Walmart, Kroger, and Costco typically offer the best cash prices.
Hydrochlorothiazide belongs to a class of medications called thiazide diuretics. It's one of the most commonly prescribed first-line blood pressure medications and works by helping the kidneys remove excess sodium and water, which is a different mechanism than an ACE inhibitor, beta blocker, or calcium channel blocker — it's frequently combined with one of those other classes in a single combination pill.
Shop around. The cheapest pharmacy (Costco at $3.40) charges significantly less than the most expensive option ($11.50). A quick call can save you real money.
Ask for the generic. If your doctor prescribed the brand-name Microzide, ask your pharmacist whether the generic HCTZ is available. In most states, pharmacists can substitute a generic unless the prescriber writes 'dispense as written.'
Use a discount card. Services like GoodRx, SingleCare, and WellRx can sometimes negotiate prices lower than retail cash. The estimated GoodRx low for Hydrochlorothiazide is around $2.90.
Hydrochlorothiazide has been an inexpensive generic for decades, with no manufacturer copay card involved — the cash prices above already reflect standard low-cost generic pricing, among the lowest of any blood pressure medication class.
Coverage depends on your specific plan and formulary. Most blood pressure medications are covered under standard health insurance, typically in Tier 1 or Tier 2. If your copay is higher than the cash price above, it may be cheaper to pay out of pocket — ask your pharmacist to compare. Prior authorization is uncommon for hydrochlorothiazide given its status as a first-line, low-cost generic that most formularies place on their lowest cost-sharing tier.
Prices represent estimated retail cash prices for Hydrochlorothiazide 25mg (30-count) as of 2026. Actual prices may vary. RxCostCheck does not collect or sell your health data. Learn more →
How much does Hydrochlorothiazide cost without insurance?
Without insurance, Hydrochlorothiazide 25mg (30-count) ranges from $3.40 at Costco to $11.50. With a GoodRx discount card, the price can be as low as $2.90.
Where is the cheapest place to fill Hydrochlorothiazide?
Costco typically offers the lowest cash price at $3.40 for 30 25mg.
Is there a generic for Hydrochlorothiazide?
Yes — the generic HCTZ is available and bioequivalent to Microzide. Ask your pharmacist to dispense the generic to save money.
What if my insurance doesn't cover Hydrochlorothiazide at all?
Ask your prescriber whether a covered therapeutic alternative in the same drug class exists, or ask your pharmacist about a formulary exception or medical-necessity appeal — some plans will cover an otherwise-excluded drug once that documentation is on file. In the meantime, the cash and discount-card pricing shown above is usually the fastest fallback.
Does a 90-day supply of Hydrochlorothiazide cost less than three 30-day fills?
Often, yes — many pharmacies and insurance plans price a 90-day fill at a lower effective per-dose cost than separate 30-day fills, and some mail-order pharmacy benefits are built specifically around 90-day supplies. Ask your pharmacist or insurer whether a 90-day option is available for this medication before assuming the count shown above is your only choice.
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