50mcg · 30-count · Thyroid · Brand: Synthroid · Generic available
| Pharmacy | Cash Price | Per-30-Day Equiv. |
|---|---|---|
| Walmart Cheapest | $4.00 | $4.00 |
| Costco | $4.00 | $4.00 |
| Kroger | $5.00 | $5.00 |
| Target | $5.50 | $5.50 |
| Rite Aid | $14.50 | $14.50 |
| CVS | $14.99 | $14.99 |
| Walgreens | $15.50 | $15.50 |
The generic form of Levothyroxine (Levothyroxine Na) contains the same active ingredient and is bioequivalent to the brand. Ask your pharmacist to dispense the generic — it works the same way at a fraction of the cost.
Tip: In most states, pharmacists can substitute a generic unless your prescriber writes "dispense as written" (DAW).
Levothyroxine is prescribed to treat hypothyroidism by supplementing thyroid hormone levels. It is sold under the brand name Synthroid and is available as the generic Levothyroxine Na. A standard supply is 30 50mcg.
Pharmacy pricing is not regulated in the United States, so retailers set their own cash prices. Large retailers like Walmart and Costco typically offer lower prices on generics because they use prescriptions as a traffic driver. Chain pharmacies like CVS and Walgreens tend to charge significantly more.
Thyroid medications require careful dosing. Generic levothyroxine is significantly cheaper than brand-name Synthroid, though some physicians prefer the brand for consistency.
Levothyroxine belongs to a class of medications called thyroid hormone replacements — it's the generic, synthetic version of the T4 hormone that a healthy thyroid produces on its own, prescribed when the thyroid isn't making enough. Because absorption can vary slightly between manufacturers, some patients and prescribers prefer to stay on the same generic manufacturer or the brand-name version once their dose is stabilized — ask your pharmacist whether your pharmacy can keep you on a consistent manufacturer rather than switching between suppliers at each refill.
Shop around. The cheapest pharmacy (Walmart at $4.00) charges significantly less than the most expensive option ($15.50). A quick call can save you real money.
Ask for the generic. If your doctor prescribed the brand-name Synthroid, ask your pharmacist whether the generic Levothyroxine Na is available. In most states, pharmacists can substitute a generic unless the prescriber writes 'dispense as written.'
Use a discount card. Services like GoodRx, SingleCare, and WellRx can sometimes negotiate prices lower than retail cash. The estimated GoodRx low for Levothyroxine is around $3.40.
Because Levothyroxine is a generic medication, manufacturer-sponsored copay savings cards — the kind commonly offered for newer, brand-name drugs — generally aren't available for it. Synthroid's manufacturer typically doesn't offer a savings card once generic competition exists, though it's worth checking their site directly if your prescriber specifically writes for the brand product. For most patients filling the generic, the discount-card and pharmacy membership options described above are the more realistic way to lower cost.
Coverage depends on your specific plan and formulary. Most thyroid medications are covered under standard health insurance, typically in Tier 1 or Tier 2. If your copay is higher than the cash price above, it may be cheaper to pay out of pocket — ask your pharmacist to compare. Thyroid hormone replacement is rarely subject to prior authorization and is typically placed on a low cost-sharing tier by most insurance plans, since it's a decades-old, foundational treatment for hypothyroidism.
Prices represent estimated retail cash prices for Levothyroxine 50mcg (30-count) as of 2026. Actual prices may vary. RxCostCheck does not collect or sell your health data. Learn more →
How much does Levothyroxine cost without insurance?
Without insurance, Levothyroxine 50mcg (30-count) ranges from $4.00 at Walmart to $15.50. With a GoodRx discount card, the price can be as low as $3.40.
Where is the cheapest place to fill Levothyroxine?
Walmart typically offers the lowest cash price at $4.00 for 30 50mcg.
Is there a generic for Levothyroxine?
Yes — the generic Levothyroxine Na is available and bioequivalent to Synthroid. Ask your pharmacist to dispense the generic to save money.
What if my insurance doesn't cover Levothyroxine at all?
Ask your prescriber whether a covered therapeutic alternative in the same drug class exists, or ask your pharmacist about a formulary exception or medical-necessity appeal — some plans will cover an otherwise-excluded drug once that documentation is on file. In the meantime, the cash and discount-card pricing shown above is usually the fastest fallback.
Does a 90-day supply of Levothyroxine cost less than three 30-day fills?
Often, yes — many pharmacies and insurance plans price a 90-day fill at a lower effective per-dose cost than separate 30-day fills, and some mail-order pharmacy benefits are built specifically around 90-day supplies. Ask your pharmacist or insurer whether a 90-day option is available for this medication before assuming the count shown above is your only choice.
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