25mcg · 30-count · Thyroid · Brand: Cytomel · Generic available
| Pharmacy | Cash Price | Per-30-Day Equiv. |
|---|---|---|
| Costco Cheapest | $7.00 | $7.00 |
| Walmart | $8.00 | $8.00 |
| Kroger | $9.00 | $9.00 |
| Target | $9.25 | $9.25 |
| Rite Aid | $18.50 | $18.50 |
| CVS | $19.99 | $19.99 |
| Walgreens | $21.00 | $21.00 |
The generic form of Liothyronine (Liothyronine Na) contains the same active ingredient and is bioequivalent to the brand. Ask your pharmacist to dispense the generic — it works the same way at a fraction of the cost.
Tip: In most states, pharmacists can substitute a generic unless your prescriber writes "dispense as written" (DAW).
Liothyronine is prescribed to treat hypothyroidism by supplementing thyroid hormone levels. It is sold under the brand name Cytomel and is available as the generic Liothyronine Na. A standard supply is 30 25mcg.
Pharmacy pricing is not regulated in the United States, so retailers set their own cash prices. Large retailers like Walmart and Costco typically offer lower prices on generics because they use prescriptions as a traffic driver. Chain pharmacies like CVS and Walgreens tend to charge significantly more.
Thyroid medications require careful dosing. Generic levothyroxine is significantly cheaper than brand-name Synthroid, though some physicians prefer the brand for consistency.
Liothyronine belongs to a class of medications called thyroid hormone replacements. Unlike levothyroxine (T4), it supplies the T3 form of thyroid hormone directly, and is sometimes prescribed alongside or instead of T4 therapy for patients who don't feel fully well on T4 alone. Because T3 has a shorter half-life and a narrower margin between too little and too much, dosing changes are typically made cautiously by an endocrinologist or prescriber rather than adjusted based on cost.
Shop around. The cheapest pharmacy (Costco at $7.00) charges significantly less than the most expensive option ($21.00). A quick call can save you real money.
Ask for the generic. If your doctor prescribed the brand-name Cytomel, ask your pharmacist whether the generic Liothyronine Na is available. In most states, pharmacists can substitute a generic unless the prescriber writes 'dispense as written.'
Use a discount card. Services like GoodRx, SingleCare, and WellRx can sometimes negotiate prices lower than retail cash. The estimated GoodRx low for Liothyronine is around $6.20.
Because Liothyronine is a generic medication, manufacturer-sponsored copay savings cards — the kind commonly offered for newer, brand-name drugs — generally aren't available for it. Cytomel's manufacturer typically doesn't offer a savings card once generic competition exists, though it's worth checking their site directly if your prescriber specifically writes for the brand product. For most patients filling the generic, the discount-card and pharmacy membership options described above are the more realistic way to lower cost.
Coverage depends on your specific plan and formulary. Most thyroid medications are covered under standard health insurance, typically in Tier 1 or Tier 2. If your copay is higher than the cash price above, it may be cheaper to pay out of pocket — ask your pharmacist to compare. Liothyronine is less commonly prescribed than levothyroxine and some plans place it on a higher cost-sharing tier or request documentation that levothyroxine alone wasn't sufficient — ask your pharmacist whether prior authorization applies to your plan.
Prices represent estimated retail cash prices for Liothyronine 25mcg (30-count) as of 2026. Actual prices may vary. RxCostCheck does not collect or sell your health data. Learn more →
How much does Liothyronine cost without insurance?
Without insurance, Liothyronine 25mcg (30-count) ranges from $7.00 at Costco to $21.00. With a GoodRx discount card, the price can be as low as $6.20.
Where is the cheapest place to fill Liothyronine?
Costco typically offers the lowest cash price at $7.00 for 30 25mcg.
Is there a generic for Liothyronine?
Yes — the generic Liothyronine Na is available and bioequivalent to Cytomel. Ask your pharmacist to dispense the generic to save money.
What if my insurance doesn't cover Liothyronine at all?
Ask your prescriber whether a covered therapeutic alternative in the same drug class exists, or ask your pharmacist about a formulary exception or medical-necessity appeal — some plans will cover an otherwise-excluded drug once that documentation is on file. In the meantime, the cash and discount-card pricing shown above is usually the fastest fallback.
Does a 90-day supply of Liothyronine cost less than three 30-day fills?
Often, yes — many pharmacies and insurance plans price a 90-day fill at a lower effective per-dose cost than separate 30-day fills, and some mail-order pharmacy benefits are built specifically around 90-day supplies. Ask your pharmacist or insurer whether a 90-day option is available for this medication before assuming the count shown above is your only choice.
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