50mcg · 30-count · Thyroid · Brand: Synthroid
| Pharmacy | Cash Price | Per-30-Day Equiv. |
|---|---|---|
| Costco Cheapest | $30.00 | $30.00 |
| Walmart | $34.00 | $34.00 |
| Target | $34.50 | $34.50 |
| Kroger | $35.00 | $35.00 |
| Rite Aid | $38.00 | $38.00 |
| CVS | $38.99 | $38.99 |
| Walgreens | $40.00 | $40.00 |
Synthroid is prescribed to treat hypothyroidism by supplementing thyroid hormone levels. It is sold under the brand name Synthroid. A standard supply is 30 50mcg.
Pharmacy pricing is not regulated in the United States, so retailers set their own cash prices. Large retailers like Walmart and Costco typically offer lower prices on generics because they use prescriptions as a traffic driver. Chain pharmacies like CVS and Walgreens tend to charge significantly more.
Thyroid medications require careful dosing. Generic levothyroxine is significantly cheaper than brand-name Synthroid, though some physicians prefer the brand for consistency.
Synthroid belongs to a class of medications called thyroid hormone replacements. It's a synthetic version of the T4 hormone (levothyroxine) that a healthy thyroid produces on its own, prescribed when the thyroid isn't making enough. Knowing the drug class matters when you're comparing cost, since the generic active ingredient, levothyroxine, is sold under several other brand names beyond Synthroid — always run any brand-vs-generic switch through your doctor rather than deciding based on price alone.
Shop around. The cheapest pharmacy (Costco at $30.00) charges significantly less than the most expensive option ($40.00). A quick call can save you real money.
Use a discount card. Services like GoodRx, SingleCare, and WellRx can sometimes negotiate prices lower than retail cash. The estimated GoodRx low for Synthroid is around $26.00.
Because Synthroid has been on the market for decades and already sits at a relatively low cash price compared to newer specialty drugs, manufacturer copay cards are less commonly advertised for it than for newer brand-name medications. If cost is still a concern, ask your doctor whether a generic levothyroxine prescription is appropriate for you — some patients are kept on brand-name Synthroid specifically for dosing consistency, so this is a conversation for your prescriber, not a decision to make from a price page alone.
Coverage depends on your specific plan and formulary. Most thyroid medications are covered under standard health insurance, typically in Tier 1 or Tier 2. If your copay is higher than the cash price above, it may be cheaper to pay out of pocket — ask your pharmacist to compare. Thyroid hormone replacement is rarely subject to prior authorization and is typically placed on a low cost-sharing tier by most insurance plans, since it's a decades-old, foundational treatment for hypothyroidism rather than a newer specialty drug.
Prices represent estimated retail cash prices for Synthroid 50mcg (30-count) as of 2026. Actual prices may vary. RxCostCheck does not collect or sell your health data. Learn more →
How much does Synthroid cost without insurance?
Without insurance, Synthroid 50mcg (30-count) ranges from $30.00 at Costco to $40.00. With a GoodRx discount card, the price can be as low as $26.00.
Where is the cheapest place to fill Synthroid?
Costco typically offers the lowest cash price at $30.00 for 30 50mcg.
Is there a generic for Synthroid?
As of 2026, Synthroid (Synthroid) does not have an FDA-approved generic. Ask your doctor about therapeutic alternatives.
What if my insurance doesn't cover Synthroid at all?
Ask your prescriber whether a covered therapeutic alternative in the same drug class exists, or ask your pharmacist about a formulary exception or medical-necessity appeal — some plans will cover an otherwise-excluded drug once that documentation is on file. In the meantime, the cash and discount-card pricing shown above is usually the fastest fallback.
Does a 90-day supply of Synthroid cost less than three 30-day fills?
Often, yes — many pharmacies and insurance plans price a 90-day fill at a lower effective per-dose cost than separate 30-day fills, and some mail-order pharmacy benefits are built specifically around 90-day supplies. Ask your pharmacist or insurer whether a 90-day option is available for this medication before assuming the count shown above is your only choice.
Compare All Drug Prices
Use our full tool to compare 100+ medications across 7 pharmacy chains.
Compare All Drugs →